Ayahuasca is a South American psychoactive brew, traditionally used by Indigenous cultures and folk healers in the Amazon and Orinoco basins for spiritual ceremonies, divination, and healing a variety of psychosomatic complaints.
Ayahuasca has also been studied for the treatment of addictions and shown to be effective, with lower Addiction Severity Index scores seen in users of ayahuasca compared to controls.
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and pain management.
Ketamine's therapeutic effects offer a potential alternative treatment for depression, suicidal ideation, SUD, and PTSD.
3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, and molly or mandy, is a potent empathogen–entactogen with stimulant and minor psychedelic properties.
MDMA, known as Ecstasy or Molly, can bring relief when paired with talk therapy to those with severe PTSD